11 November 2021

Ischaemic colitis caused by polyethylene glycol with ascorbic acid bowel preparation agent

Soo In Choi, Jeongmin Choi - BMJ, 2021


Various bowel preparation agents have been developed for effective and safe bowel cleansing before colonoscopy. Polyethylene glycol (PEG) is widely used in the elderly. A 2 L PEG solution with ascorbic acid (PEG-Asc) was developed to reduce the volume of standard 4 L PEG.

Several cases of ischaemic colitis caused by stimulant laxatives or hyperosmolar bowel preparation agents have been reported.1–5 However, PEG-Asc-induced ischaemic colitis has rarely been reported. Here, we report a rare case of ischaemic colitis after administration of PEG-Asc.

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