1 June 2020
Ellison, E. E., Nagalakshmi, U., Gamo, M.E., Huang, P., Dinesh-Kumar, S. P., Voytas, D. F. - Nature Plants, 2020
An in planta gene editing approach was developed wherein Cas9 transgenic plants are infected with an RNA virus that expresses single guide RNAs (sgRNAs). The sgRNAs are augmented with sequences that promote cell-to-cell mobility. Mutant progeny are recovered in the next generation at frequencies ranging from 65 to 100%; up to 30% of progeny derived from plants infected with a virus expressing three sgRNAs have mutations in all three targeted loci.
Read the entire publicationBy submitting this form, you are consenting to receive marketing emails from: The Crop Science Centre, Lawrence Weaver Rd, Cambridge, CB3 0LE, GB. You can revoke your consent to receive emails at any time by using the SafeUnsubscribe® link, found at the bottom of every email. Emails are serviced by Constant Contact.
