Alexis L Sperling

Alexis L Sperling

Postdoctoral research associate

Research groups: Plant-parasitic interactions

Alexis L Sperling


I started off at the University of Victoria (Canada) in biochemistry and biology and then moved to KTH (Sweden) for my masters in bioreactors and protein engineering. I did my PhD at the University of Cambridge (UK) in the Zoology Department on epithelial patterning in Drosophila eggs. My first postdoc was on centrosome migration in Drosophila eggs and my second postdoc was on the genetic basis of parthenogenesis in Drosophila. I am excited to take my knowledge in cell and developmental biology into my new research on the cell molecular biology of plant parasite interactions, specifically on effector biogenesis in nematodes. I am working towards building knowledge of the fundamental biology of pathogenic nematodes in order to gain insight into how we can prevent pathogenic nematode infections.



The SUbventral-Gland master Regulator (SUGR) of nematode virulence

Date: 12 February 2024

Contributors: Clement Pellegrin, Anika Damm, Alexis L. Sperling, Beth Molloy, Dio S. Shin, Jonathan Long, Paul Brett, Andrea Díaz-Tendero Bravo, Sarah Jane Lynch, Beatrice Senatori, Paulo Vieira, Joffrey Mejias, Anil Kumar, Rick E. Masonbrink, Tom R. Maier, Thomas J. Baum, Sebastian Eves-van den Akker

Journal: Biorxiv


The origin, deployment, and evolution of a plant-parasitic nematode effectorome

Date: 5 January 2024

Contributors: Beth Molloy, Dio S. Shin, Jonathan Long, Clement Pellegrin, Beatrice Senatori, Paulo Vieira, Peter Thorpe, Anika Damm, Mariam Ahmad, Kerry Vermeulen, Lida Derevnina, Siyuan Wei, Alexis Sperling, Estefany Reyes Estévez, Samuel Bruty, Victor Hugo Moura de Souza, Olaf Prosper Kranse, Tom Maier, Thomas Baum, Sebastian Eves-van den Akker

Journal: Biorxiv


A genetic basis for facultative parthenogenesis in Drosophila

Date: 11 September 2023

Contributors: Alexis L. Sperling, Daniel K. Fabian, Erik K. Garrison, and David M. Glover.

Journal: Current Biology


Parthenogenesis in dipterans: a genetic perspective.

Date: 29 March 2023

Contributors: Alexis L. Sperling and David M. Glover.

Journal: Royal Society B: Biological Sciences.


The careful control of Polo kinase by APC/C-Ube2C ensures the intercellular transport of germline centrosomes during Drosophila oogenesis

Date: 30 June 2021

Contributors: Alexis L. Braun, Francesco Meghini, Gema Villa-Fombuena, Morgane Guermont, Elisa M. Fernandez, Zhang Qian, Maria D. Martin-Bermudo, Acaimo Gonzalez-Reyes, David M. Glover, Yuu Kimata

Journal: Open Biology

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