Crop Science Centre

Driven by impact, fuelled by excellence

 Natasha Yelina

Natasha Yelina

Head of the Crop Breeding Technologies group
Crop breeding technologies


Prior to joining the Crop Science Centre Natasha worked on the fundamental aspects of plant meiotic recombination, genetics, epigenetics and plant pathology at the Department of Plant Sciences within the University of Cambridge, the Sainsbury laboratory in Norwich and Moscow State University in Russia.


Nucleosomes and DNA methylation shape meiotic DSB frequency in Arabidopsis thaliana transposons and gene regulatory regions.

Choi K, Zhao X, Tock AJ, Lambing C, Underwood CJ, Hardcastle TJ, Serra H, Kim J, Cho HS, Kim J, Ziolkowski PA, Yelina NE, Hwang I, Martienssen RA, Henderson IR.Genome Res. 2018 Apr;28(4):532-546. doi: 10.1101/gr.225599.117. Epub 2018 Mar 12.PMID: 29530928 Free PMC article.

 Quantification and Sequencing of Crossover Recombinant Molecules from Arabidopsis Pollen DNA.

Choi K, Yelina NE, Serra H, Henderson IR.Methods Mol Biol. 2017;1551:23-57. doi: 10.1007/978-1-4939-6750-6_2.PMID: 28138839

 Recombination Rate Heterogeneity within Arabidopsis Disease Resistance Genes.

Choi K, Reinhard C, Serra H, Ziolkowski PA, Underwood CJ, Zhao X, Hardcastle TJ, Yelina NE, Griffin C, Jackson M, Mézard C, McVean G, Copenhaver GP, Henderson IR.PLoS Genet. 2016 Jul 14;12(7):e1006179. doi: 10.1371/journal.pgen.1006179. eCollection 2016 Jul.PMID: 27415776 Free PMC article.

 DNA methylation epigenetically silences crossover hot spots and controls chromosomal domains of meiotic recombination in Arabidopsis.

Yelina NE, Lambing C, Hardcastle TJ, Zhao X, Santos B, Henderson IR.Genes Dev. 2015 Oct 15;29(20):2183-202. doi: 10.1101/gad.270876.115.PMID: 26494791 Free PMC article.

 Juxtaposition of heterozygous and homozygous regions causes reciprocal crossover remodelling via interference during Arabidopsis meiosis.

Ziolkowski PA, Berchowitz LE, Lambing C, Yelina NE, Zhao X, Kelly KA, Choi K, Ziolkowska L, June V, Sanchez-Moran E, Franklin C, Copenhaver GP, Henderson IR.Elife. 2015 Mar 27;4:e03708. doi: 10.7554/eLife.03708.PMID: 25815584 Free PMC article.

 Epigenetic control of meiotic recombination in plants.

Yelina N, Diaz P, Lambing C, Henderson IR.Sci China Life Sci. 2015 Mar;58(3):223-31. doi: 10.1007/s11427-015-4811-x. Epub 2015 Feb 5.PMID: 25651968 Free article. Review.

 High-throughput analysis of meiotic crossover frequency and interference via flow cytometry of fluorescent pollen in Arabidopsis thaliana.

Yelina NE, Ziolkowski PA, Miller N, Zhao X, Kelly KA, Muñoz DF, Mann DJ, Copenhaver GP, Henderson IR.Nat Protoc. 2013 Nov;8(11):2119-34. doi: 10.1038/nprot.2013.131. Epub 2013 Oct 10.PMID: 24113785

 Arabidopsis meiotic crossover hot spots overlap with H2A.Z nucleosomes at gene promoters.

Choi K, Zhao X, Kelly KA, Venn O, Higgins JD, Yelina NE, Hardcastle TJ, Ziolkowski PA, Copenhaver GP, Franklin FC, McVean G, Henderson IR.Nat Genet. 2013 Nov;45(11):1327-36. doi: 10.1038/ng.2766. Epub 2013 Sep 22.PMID: 24056716 Free PMC article.

 Epigenetic remodeling of meiotic crossover frequency in Arabidopsis thaliana DNA methyltransferase mutants.

Yelina NE, Choi K, Chelysheva L, Macaulay M, de Snoo B, Wijnker E, Miller N, Drouaud J, Grelon M, Copenhaver GP, Mezard C, Kelly KA, Henderson IR.PLoS Genet. 2012;8(8):e1002844. doi: 10.1371/journal.pgen.1002844. Epub 2012 Aug 2.PMID: 22876192 Free PMC article.

 Putative Arabidopsis THO/TREX mRNA export complex is involved in transgene and endogenous siRNA biosynthesis.

Yelina NE, Smith LM, Jones AM, Patel K, Kelly KA, Baulcombe DC.Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13948-53. doi: 10.1073/pnas.0911341107. Epub 2010 Jul 15.PMID: 20634427 Free PMC article.

Epigenetic control of meiotic recombination in plants
Natasha Yelina, Patrick Diaz, Christophe Lambing, Ian R Henderson Science China. Life sciences 2015-02-06 pmid:25651968 doi:10.1007/s11427-015-4811-x